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- Newsgroups: talk.abortion
- Path: sparky!uunet!mnemosyne.cs.du.edu!nyx!mcochran
- From: mcochran@nyx.cs.du.edu (Mark A. Cochran)
- Subject: Re: Myelin (Was Re: Spoken Like a True ProLifer)
- Message-ID: <1993Jan22.035802.8755@mnemosyne.cs.du.edu>
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- References: <1993Jan20.062913.13725@mnemosyne.cs.du.edu> <1993Jan21.034431.24481@organpipe.uug.arizona.edu> <JBATES.93Jan21035438@pinocchio.encore.com>
- Date: Fri, 22 Jan 93 03:58:02 GMT
- Lines: 121
-
- In article <JBATES.93Jan21035438@pinocchio.encore.com> jbates@encore.com (John W. Bates) writes:
- >
- >By the way, I just started catching up on this thread, and noticed
- >that earlier Steve provided a reference to the same research I did,
- >except he did it much earlier than I did. My apologies for posting
- >it again. I could cancel the article, but I don't feel like it. Nyah.
- >
- >In article <1993Jan21.034431.24481@organpipe.uug.arizona.edu> sfm@manduca.neurobio.arizona.edu (Stephen Matheson) writes:
- >> From article <1993Jan20.062913.13725@mnemosyne.cs.du.edu>, by
- >> mcochran@nyx.cs.du.edu (Mark A. Cochran):
- >
- >[much deletion.]
- >
- >>>>>>>>My contention remains: large segments of the nervous system
- >>>>>>>>function beautifully without myelin. Myelin has a very
- >>>>>>>>specific purpose: it allows for fast conduction of impulses.
- >>>>>>>>It must not be indispensible for function, because it is
- >>>>>>>>anything but ubiquitous. While it is reasonable to guess that
- >>>>>>>>speedy conduction would be advantageous to a complex network,
- >>>>>>>>it seems reasonable to assume that one can design a network
- >>>>>>>>without it.
- >
- >>>>>>> Kind of like trying to build a hypercube out of a bunch of
- >>>>>>> C=64's? I'm sure it can be done, but would it actually be
- >>>>>>> capable of performing any resonable work?
- >
- >>>>>>Huh? Can you provide some hypercube and C=64 references? :-) Are
- >>>>>>they available on request?
- >
- >>>>> A hypercube (as I understand it, but it's not my field at all) is
- >>>>> a bunch of cross-linked multi-processor computers that tries to
- >>>>> simulate the neural system by multiple cross-links. The C=64 is
- >>>>> the ancient Commodore 64 that people have always laughed about.
- >>>>> It would be interesting (funny even) to see what would happen if
- >>>>> Commodore got hte idea to try this for real. :)
- >
- >>>>Wow. Mark is a mrpmsysp UGR futrvits (Mark's occupation has been
- >>>>encrypted at his request; decoder available from T.S.A.K.C. BBS)
- >>>>*and* a neural network guru. That's amazing.
- >
- >>> Huh UH! No Way! See right up there where I specifically deny any
- >>> expertise in this area? I've read a litle bit, and talked to
- >>> people, but no *way* are you goin to get me to play neural network
- >>> sysadmin here. ;)
- >
- >> Very well. You're the one who brought it up. I wonder if John
- >> Bates can get enough free time to comment on the applicability of
- >> your analogy.
- >
- >Sorry, Mark, but you've got things a little mixed up. In networking
- >lingo, hypercubes are a network designed for supercomputing, with
- >a node at each vertex connecting to each neighboring vertex. It's not
- >related to neural networks at all. The closest neural network design
- >I can think of is James Anderson's "brain state in a box", in which
- >each output pattern is a vertex of an n-dimensional box. Nice model
- >for associative memory, but n tends to have to be very large (in
- >computational terms) for it to be useful.
- >
- It's a good thing I made sure to deny any real knowledge of
- hyper-cubes then, isn't it? :)
- I still bet you can't build one out of C=64's though.... :)
-
- >I've been leary of bringing models into this discussion, since it is
- >often hard to relate models of neural networks to actual neural
- >networks. But now, let me refer to a model by Stanislas Dehaene and
- >Jean-Pierre Changeux, which simulated the performance of human
- >infants in Piaget's A not B task. Their results approximated the
- >performance of human infants.
- >
- >The interesting part of the experiment, though, was that they varied
- >the amount of "noise" that the network received. At high levels
- >of noise, the network performed at the level of a 7-month old infant,
- >but at low levels, it performed at the level of a 12-month old infant.
- >Noise levels seemed to correspond to the development of myelin in
- >the frontal lobes.
- >(from the _Journal of Cognitive Neuroscience_ 1:3, S. Dehaene and J.P.
- >Changeux, A simple model of prefontal cortex function: delayed
- >response tasks)
- >
- Interesting. If they were able to jump the noise level around to
- approximate various developmental stages, I wonder if they could/did
- jump it up to a level that would approximate that development of, say,
- a 22 week fetus?
- Be interesting to see the results if they did. It could shed some
- light on this subject, at least.
-
- [Crabs and Squid deleted, since I've already had lunch]
-
- >>>>> The resonable work in question, though, is thought. Just as you
- >>>>> can't use a 4 bit 16K RAM computer as an effective file server, I
- >>>>> don't see how you cna use the similarly limited abilities ofthe
- >>>>> pre-myelinated neural system as a 'thought server'.
- >
- >>>>I'm reserving my judgment on the matter for a time when we know
- >>>>more about all the issues involved. The hypomyelinated mice
- >>>>discussed later in the post may be our best window into this issue.
- >>>>In the meantime, it must be obvious to everyone reading this thread
- >>>>(all 3 of us :-) that neither of us has any clue about whether
- >>>>myelin is necessary or not. I think that there is at least a fair
- >>>>amount of information on the biological side that suggests that
- >>>>myelin is not as central as some claim. On the other hand, your
- >>>>arguments about the presumed complexity of the network are
- >>>>certainly thought-provoking (there's that smell again...myelin
- >>>>burning or something).
- >
- >Yes. The major problem that we have in modelling brain processes is
- >the complexity of the whole thing. I mean, our supercomputers have
- >problems with 2-3000 neuron models. Massively parallel systems
- >reach the 16-32000 neuron level. How much of the brain is actually
- >dedicated to thought? Maybe what, 10^10 neurons?
- >
- I recall reading we'd need a computer the size of (something like)
- Manhatten to approximate the brain. Does that sound like a resonable
- size?
-
-
- --
- Mark Cochran merlin@eddie.ee.vt.edu
- These are the views of my employer, your employer, your government, the
- Church of your choice, and the Ghost of Elvis. So there.
- Member, T.S.A.K.C.
-