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- From: wcalvin@stein.u.washington.edu (William Calvin)
- Newsgroups: bionet.neuroscience
- Subject: Re: What are neural columns?
- Message-ID: <1jhj16INNjuk@shelley.u.washington.edu>
- Date: 19 Jan 93 18:58:46 GMT
- References: <1993Jan19.012354.15238@gserv1.dl.ac.uk>
- Distribution: bionet
- Organization: University of Washington
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- NNTP-Posting-Host: stein.u.washington.edu
-
- tbrannon@CSEE.Lehigh.Edu (tbrannon) writes:
- >Can someone provide a brief overview of what neural columns are?
-
- The newer parts of cerebral cortex seem to have two levels of "modular"
- organization, about 300 minicolumns (about 30-50 microns in diameter, possibly
- corresponding to those lined-up cells you see in Nissl stains, radiating
- up from the white matter) nestled inside a macrocolumn (maybe 0.5 mm in size).
-
- Physiologically, they are defined by clustering of response types: a
- typical minicolumn is the orientation column of visual cortex, all of
- whose neurons seemingly interested in lines/edges at about the same
- (within 10 degrees) orientation. A typical macrocolumn is the ocular
- dominance column, best defined in layer IVc whose cells are only
- responsive to one eye; move laterally and you find another 0.5mm wide
- group that are interested in the other eye.
-
- Some other collections have been called "columns" such as Hubel & Wiesel's
- hypercolumns (essentially two ocular dominance columns, left and right,
- taken together, each of which has a full range of orientation columns
- embedded in it). Somatosensory cortex is where macrocolumns were
- discovered in the first place by Mountcastle in 1957, where modalities
- (skin vs joint sensation, for instance) cluster. They have been seen in
- several of the secondary visual areas, specializing in various kinds of
- feature detection. There is no general theory for what association cortex
- might be doing with this kind of organization, though I find myself working
- on one (and NO, there is nothing on this in my books such as CEREBRAL
- SYMPHONY or ASCENT OF MIND; it's all happened recently, e.g., Soc. Neurosci.
- Abstr. 18:214.18, 1992).
-
- William H. Calvin WCalvin@U.Washington.edu
- University of Washington NJ-15
- Psychiatry & Behavioral Sciences
- Seattle, Washington 98195 FAX:1-206-720-1989
-