home *** CD-ROM | disk | FTP | other *** search
- Path: sparky!uunet!zaphod.mps.ohio-state.edu!uwm.edu!daffy!uwvax!zazen!uwec.edu!nyeda
- From: nyeda@cnsvax.uwec.edu (David Nye)
- Newsgroups: sci.med
- Subject: Re: Deprenyl
- Message-ID: <1992Nov18.205655.2430@cnsvax.uwec.edu>
- Date: 18 Nov 92 20:56:55 -0600
- References: <1992Nov16.235730.2369@cnsvax.uwec.edu> <1992Nov17.181034.13282@spdcc.com> <1992Nov17.202906.2411@cnsvax.uwec.edu> <1992Nov18.181219.21367@spdcc.com>
- Organization: University of Wisconsin Eau Claire
- Lines: 16
-
- In article <1992Nov18.181219.21367@spdcc.com>, dyer@spdcc.com (Steve Dyer) writes:
-
- > The evidence for the utility of tacrine in Alzheimer's is substantially
- > less than selegiline in Parkinson's (however minor a therapeutic advance
- > selegiline is), and tacrine tends to be hepatotoxic. I got the impression
- > that the manufacturers of tacrine were going to test, test, test until
- > they were able to show even the most minor beneficial result.
-
- There was just another study on tacrine in one of the main neurology
- journals (I forget which one), suggesting definite but mild efficacy.
- Side effects were also a big problem. In contrast, there is not a
- single study to my reading that proves that selegiline has anything
- other than a weak symptomatic benefit.
-
- David Nye
- nyeda@cnsvax.uwec.edu
-