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- Path: sparky!uunet!ogicse!decwrl!zazen!uwec.edu!nyeda
- From: nyeda@cnsvax.uwec.edu (David Nye)
- Newsgroups: sci.med
- Subject: Deprenyl
- Message-ID: <1992Nov16.235730.2369@cnsvax.uwec.edu>
- Date: 16 Nov 92 17:57:30 GMT
- Article-I.D.: cnsvax.1992Nov16.235730.2369
- Organization: University of Wisconsin Eau Claire
- Lines: 16
-
- Deprenyl is an irreversible inhibitor of MAO-B purported to slow the
- progression of Parkinson's disease. It as been in use in Europe for
- many years as an adjunct in the symptomatic treatment of PD. The
- Europeans have, I am told, not been terribly excited about the drug.
- The studies that have purported to show slowing of the progression of
- the disease have methodological problems. It is usually given twice
- a day. A month's worth costs around $100.
-
- My question/suggestion: since it irreversibly inhibits MAO-B and has
- a half life of well over a month, why not give only two tablets a
- month? That is, presuming that one thinks it should be given at all
- if it's efficacy hasn't been proven conclusively. It sure would be a
- heck of a lot cheaper. Thoughts?
-
- David Nye
- nyeda@cnsvax.uwec.edu
-