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- From: brandon@caldonia.nlm.nih.gov (Brandon Brylawski)
- Subject: Re: asthma prednisone allergy
- Message-ID: <1993Jan27.152848.7114@nlm.nih.gov>
- Sender: news@nlm.nih.gov
- Organization: National Library of Medicine
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- References: <11300@vtserf.cc.vt.edu>
- Date: Wed, 27 Jan 93 15:28:48 GMT
- Lines: 66
-
- stellr@smyrna (Ray Stell) writes:
- : My 10 year-old son has had two exercise indused asthma attacks
- : before this year. He has had three attacks since last summer
- : that were chronic in nature (not an event, but rather his lungs
- : developed a wheeze that progressively got worse). Those three
- : times his gp prescribed a strong/week-long cycle of prednisone.
- : Each time this cleared his lungs.
- :
- : The second event/treatment, last October, left him with a
- : chronic stomach ache, a known side-effect (we guess the
- : prednisone did it, they did an upper gi, in December, no ulcer
- : detected).
- :
- : "The Complete Book of Children's Allergies, A Guide for Parents",
- : by B. Robert Feldman, M. D., from Columbia Presbyterian Med
- : Center, ISBN 0-8129-1211-X, lists the side-effects of extended
- : steriod use, and my son showed most of them within days, weight
- : gain (5 lbs, in a week), moon face, headache, insomnia, bad
- : stomach ache, etc. The text says that this is not supposed to
- : happen until after two weeks of use.
- :
- : So, why does he get these side-effects? Is the dose to strong?
- : I assume this will happen again, in the spring, when the plants
- : are active, he has always had allergies to various pollens,
- : dust, molds, etc. Should we avoid prednisone? If so, when his
- : lungs are stressed, what do we do? He already takes the daily
- : inhaler of cromolyn sodium (Intal) and uses albuterol sulfate
- : (Ventolin) when he begins wheezing. He has taken the Intal,
- : daily for the last year and a half.
- :
- : I don't want to give him the steriod again. What are the
- : alternatives?
- : ======================================================================
- : Ray Stell stellr@smyrna.cc.vt.edu (703) 231-4109
-
- Some people are much more sensitive to steroid side-effects than others, and your
- son may be among these. It's hard to say whether the dose is appropriate without
- knowing the dose and how much your son weighs, though.
-
- There are several other things you should try doing.
-
- 1. Continue using the intal regularly.
- 2. Use the ventolin one-half to one hour BEFORE exercising; many with exercise-induced
- asthma can avoid attacks by doing this.
- 3. Use the ventolin regularly (2 puffs four to six times a day) whenever he seems to
- be having an allergy attack or a cold, or is otherwise having trouble, and as needed.
- Ventolin has for most people no side effects, even when used daily, and you
- can't really overdose on it (if you use it too much, it may make your heart race or
- make you jittery, but rarely anything else).
- 4. If the above still don't help, consider a steroid inhaler (sample brand names
- azmacort, beclovent; avoid aerobid - it tastes bad). These are very effective but
- have many fewer effects than oral prednisone because the dose is MUCH smaller.
- If his problems are seasonal, he could use a steroid inhaler for just those times of
- year, which would minimize side effects as well. One note about steroid inhalers -
- brush your teeth or rinse your mouth out after every use, to avoid a yeast infection.
- 5. An overall point: make sure he's using the inhalers properly. The idea is to
- get the medicine into the lungs, not spray the back of the throat. Many patients
- put the inhaler in their mouths, spray, and inhale; this wastes most of the medicine.
- (I've even seen package inserts that say to do it this way, but they're wrong.)
- Hold the inhaler about one inch in front of your wide-open mouth. Breathe out all the
- way, then take a deep breath. Fire the inhaler AS YOU ARE BREATHING IN. Hold the
- deep breath for a few seconds, then inhale. repeat once.
-
- Good luck,
-
- Brandon Brylawski, MD
-