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- Path: sparky!uunet!ulowell!m2c!bu.edu!rpi!gatech!pitt!geb
- From: geb@cs.pitt.edu (Gordon Banks)
- Newsgroups: sci.med
- Subject: Re: What's Lorazepam
- Message-ID: <18230@pitt.UUCP>
- Date: 26 Jan 93 22:00:20 GMT
- References: <726458356.AA00522@f-454.fidonet.org> <18054@pitt.UUCP> <szikopou.727038286@cunews>
- Sender: news@cs.pitt.edu
- Reply-To: geb@cs.pitt.edu (Gordon Banks)
- Organization: Univ. of Pittsburgh Computer Science
- Lines: 41
-
- In article <szikopou.727038286@cunews> szikopou@alfred.carleton.ca (Steven Zikopoulos) writes:
- >
- >I don't see how you can use the fact that one can suffer from seizures
- >after withdrawing from an benzodiazepine as a mark of addiction. BZ's
- >supposedly potentiate GABA functioning (right?) and GABA is
- >inhibitory.
- >
- While withdrawing, not after withdrawing. The appearance of physical
- symptoms during withdrawal is one of the definitions of addictive.
- Seizures are a very excellent physical symptom.
-
- >Think about withdrawl from an optiate agonist as a paradigm case. You
- >take something like morhpine for awhile and your brain decides not to
- >produce any endogenous optiate agonists becasue you're feeding the
- >receptors with the morphine. So when you stop, you're lacking what
- >the system should have and....withdrawl. (You with me?) (a quick and
- >dirty explanation but in the interest of brevity....)
- >
-
- Right. This is why we call opiates "addictive".
-
- >
- >With respect to BZs I agree that they can be addictive (or if
- >you prefer...habit forming). What I disagree with I guess is that
- >you're using physiological markers as evidence for addiction and
- >ignoring psychological systems involved. This is especailly important
- >when discussing anxiolytic meds.
- >
- Who is ignoring psychological addiction? I was discussing physical addiction.
- There is such a thing as psychological addiction. Marijuana is
- an example of a substance that is said to be psychologically but not physically
- addictive. Benzodiazepenes and morphine are both.
-
-
-
-
- --
- ----------------------------------------------------------------------------
- Gordon Banks N3JXP | "I have given you an argument; I am not obliged
- geb@cadre.dsl.pitt.edu | to supply you with an understanding." -S.Johnson
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