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- Path: sparky!uunet!cs.utexas.edu!asuvax!ncar!noao!arizona!amethyst!organpipe.uug.arizona.edu!news
- From: sfm@manduca.neurobio.arizona.edu (Stephen Matheson)
- Newsgroups: sci.bio
- Subject: Re: MRNA
- Message-ID: <1993Jan21.041055.24779@organpipe.uug.arizona.edu>
- Date: 21 Jan 93 04:10:55 GMT
- References: <105875@netnews.upenn.edu>
- Sender: news@organpipe.uug.arizona.edu
- Organization: University of Arizona UNIX Users Group
- Lines: 32
-
- From article <105875@netnews.upenn.edu>,
- by barkdoll@lepomis.psych.upenn.edu (spacesareforthefeebleminded):
- > In article <1759@tdat.teradata.COM> swf@tools3teradata.com
- > (Stan Friesen) writes:
- >>In article <104941@netnews.upenn.edu>,
- >>rowe@pender.ee.upenn.edu (Mickey Rowe) writes:
-
- >>|> >The brain statement is based on the fact that neurons have less
- >>|> >DNA per unit weight than other kinds of cells (eggs-cluding eggs
- >>|> >and who knows what other special cases).
-
- >>|> I suspect that this is generally untrue.
-
- >>Ah, but it is in fact exactly literally true! All cells in a single
- >>body have the *same* amount of DNA (with a few wierd exception like
- >>the polytene chromosomes in the salivary glands of Drosophila).
-
- > Ah, but it is in fact exactly literally false! Class
- > switching of B cells, antigen specificity selection of immunoglobulins
- > and T cell receptor specifity all involve deletion and recombination
- > of DNA. Then of course most ("most" is just to hedge my bets) mature
- > mammalian red blood cells have NO nuclear DNA.
-
- First of all, I would argue that both your examples might be classified
- as "weird exceptions". More importantly, I am skeptical that the
- DNA rearrangements you refer to could have any measureable effect on
- the rather crude DNA-per-unit-weight measurement.
-
- --
-
- Steve Matheson Program in Neuroscience University of Arizona
- sfm@neurobio.arizona.edu
-