home *** CD-ROM | disk | FTP | other *** search
- Path: sparky!uunet!zaphod.mps.ohio-state.edu!magnus.acs.ohio-state.edu!usenet.ins.cwru.edu!po.CWRU.Edu!jxj24
- From: jxj24@po.CWRU.Edu (Jonathan Jacobs)
- Newsgroups: bionet.neuroscience
- Subject: Re: Schizophrenia and the immune system
- Date: 23 Jan 1993 04:52:03 GMT
- Organization: Case Western Reserve University, Cleveland, OH (USA)
- Lines: 45
- Message-ID: <1jqitjINN8gl@usenet.INS.CWRU.Edu>
- References: <1993Jan9.162914.11756@news.acns.nwu.edu>
- Reply-To: jxj24@po.CWRU.Edu (Jonathan Jacobs)
- NNTP-Posting-Host: slc12.ins.cwru.edu
-
-
- In a previous article, mitchm@casbah.acns.nwu.edu (Mitchell Maltenfort) says:
-
- >
- > I was recently watching a PBS "Frontline" on schizophrenia, and was
- >struck by an idea when it was mentioned that schizophrenics have certain
- >white blood cell abnormalities. Is it possible that schizophrenia is an
- >autoimmune disease?
- >
- > There is some precedent for this: myasthenia gravis is an autoimmune
- >disease in which the immune system targets the neurotransmitters that activate
- >muscle. Might schizophrenia be the result of the immune system interfering
- >with the brain functions?
- >
- > Although I have some basic knowledge of the nervous system, I don't
- >know as much about the specific condition of schizophrenia or the immune
- >system as I should to be able to evaluate this possibility. I'm just posting
- >it to get some discussion going.
- >
- >
- >Mitchell Maltenfort Northwestern Unversity Chicago, Illinois
- >
- >mgm@nwu.edu |:* Studying simulations or simulating studies *:|
- >
- >
- Mitchell,
-
- Not to be pedantic, but in myasthenia gravis the _receptors_ for the
- neurotransmitter (acetylcholine) are attacked by the immune system, not
- the neurotransmitter itself.
-
- But it is an interesting question alright. It certainly seems plausible
- enough, and god knows that there are about a zillion ways your immune
- system can turn on you when you least expect it. And there are about
- a zillion more ways that your brain can unravel on you when you least
- realize it. Actually, that sounds very depressing when I reread it, but
- it's absolutely fantastic how something so complex as an entire organism
- can actually exist. Even when it doesn't work quite right.
-
- Just remember: "It's not how well the bear dances, but that it dances at all."
-
- Jon Jacobs
- Dept. of Biomedical Engineerin' and stuff
- Case Western Reserve University
- Accept no substitutes.
-