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- From: lamontg@stein.u.washington.edu (Lamont Granquist)
- Newsgroups: sci.med
- Subject: Re: post-Prozac reactions
- Message-ID: <1992Dec24.011016.2733@u.washington.edu>
- Date: 24 Dec 92 01:10:16 GMT
- Article-I.D.: u.1992Dec24.011016.2733
- References: <1992Dec14.133117.20486@u.washington.edu> <1992Dec20.133028.10836@newstand.syr.edu> <1992Dec21.194052.1328@cbfsb.cb.att.com> <1992Dec23.085430.17591@newstand.syr.edu>
- Sender: news@u.washington.edu (USENET News System)
- Organization: 'Operation: Mindcrime'
- Lines: 34
-
- mdkline@rodan.acs.syr.edu (Mark D. Kline) writes:
-
- About Prozac and bipolar/cyclothymia: I've heard from patients that
- their doctors have mentioned a problem with fluoxetine exacerbating
- manic phases when treating a patient with one of these disorders.
-
- >Yes rage (or irritability) can be a symptom of mania or hypomania.
- >People can and do "switch" suddenly from a depressive to a manic or
- >hypomanic state while taking antidepressants - the traditional teaching
- >has been that all antidepressants can induce such a switch in susceptible
- >people. There is some talk now that perhaps its just chance, that
- >perhaps the antidepressants aren't causing the switch (its the post hoc
- >ergo propter hoc problem again...)
-
- Well, I know what mania + hypomania are. Prozac didn't make me hypomanic
- or manic. It tended to make me more amotivated, more tired, only I has
- less of a dysphoric mood about it all (kinda "happy to feel depressed" in
- a way, only I wasn't particularly happy, just not-dysphoric). Then right
- after going from 20mg/day to 40mg/day I had one episode of a flood of
- rage. never had it before, never had it since, and it was way out of
- proportion with how I emotionally felt. Chance? I really doubt it, its
- the only factor which could account for that kind of out-of-control drug-like
- state. And I've never experienced anything of a similar vien to that out-of-
- control state (even with perhaps different emotions) before or after that
- when I've been at baseline (which besides the prozac I was and had been
- for quite some time...).
-
- Of course I *am* atypical. I'm just saying don't neglect the possibility
- that Prozac could do this in a certain small number of patients.
-
- --
- Lamont Granquist lamontg@u.washington.edu
- "When dogma enters the brain, all intellectual activity ceases."
- -- Robert Anton Wilson
-