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- Path: sparky!uunet!paladin.american.edu!gatech!concert!rutgers!uwvax!zazen!uwec.edu!nyeda
- From: nyeda@cnsvax.uwec.edu (David Nye)
- Newsgroups: sci.med
- Subject: Re: Migraine Medication
- Message-ID: <1992Dec22.081828.2978@cnsvax.uwec.edu>
- Date: 22 Dec 92 14:18:28 GMT
- Organization: University of Wisconsin Eau Claire
- Lines: 27
-
- [reply to amt@linus.mitre.org]
-
- >If verapamil proved to be ineffective as a migraine prophylactic for a
- >migraine sufferer, would propranolol be any better? Are the
- >medications significantly different enough for migraine control? Would
- >their in/effectiveness depend upon the individual?
-
- Maybe, yes, and yes. There are more than a dozen different medications
- useful for migraine prophylaxis. I usually start with verapamil 240 mg
- SR at bedtime, then push the dose up to twice a day if the headaches
- aren't under control on the lower dose in a month. I like it because it
- has the lowest incidence of side effects of any of the medications for
- migraine prophylaxis. You can also use the non-sustained release
- tablets which are a good deal cheaper but have to be taken 3-4 times a
- day. If that doesn't work, I usually go to propranolol or Depakote
- next. Amitriptyline works as well as the rest of these, better if there
- is a significant tension headache component, but has the most side
- effects of the four. Amitriptyline and propranolol together is a good
- combination for particularly resistant migraines. The trick is to give
- each medication for at least a month, because they may take some time to
- start working, and slowly push the dose up until side effects prevent
- further increases. Of course, even more important than choice of a
- medication for migraine prophylaxis is to make sure that you have made
- any necessary dietary or lifestyle adjustments (see the FAQ).
-
- David Nye
- nyeda@cnsvax.uwec.edu
-