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- From: bhjelle@carina.unm.edu ()
- Subject: Re: What homing device does a virus use?
- Message-ID: <tmjq2ba@lynx.unm.edu>
- Date: Mon, 16 Nov 92 17:30:27 GMT
- Organization: University of New Mexico, Albuquerque
- References: <1e8fusINNqmc@im4u.cs.utexas.edu>
- Lines: 22
-
- In article <1e8fusINNqmc@im4u.cs.utexas.edu> turpin@cs.utexas.edu (Russell Turpin) writes:
- >-*----
- >There are several viruses (some, but not all, strains of herpes,
- >HPV, etc.) that cause sores or growths on the skin *around* the
- >mouth or the skin *around* the genitalia, though not in the mouth
- >itself or on the genitalia directly. In the case of a virus that
- >directly infects the mouth or genitalia, I can understand the
- >specificity as a preference for tissue type. But in the other
- >case, how does a virus distinguish skin *around* the genitalia
- >(for example) from skin around the belly button or around the ear?
-
- It is quite possible that skin around the genitalia differs
- from skin elsewhere in expression of a cell-surface HPV
- receptor molecule, or in an intracellular factor needed for
- HPV replication. However, there are a lot of other possible
- explanations for the apparent tropism of some HPV types to
- genital skin.
-
- Brian
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