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- too large, through gaps between the endothelial cells of the
- capillary walls. Such filtration allows blood both to deliver
- dissolved substances to cells and to pick up wastes from cells.
- The mechanism of filtration works in the following manner.
- As the blood passes from arterioles into capillary beds, the
- hydrostatic pressure in the capillaries is higher than the
- opposing osmotic pressure in the cells of the surrounding
- tissue. Such a pressure gradient causes water and dissolved
- substances to move out of the capillaries. By the time the
- blood passes from the capillaries into the venules, the
- hydrostatic pressure has fallen lower than the osmotic
- pressure of the surrounding cells. The new pressure
- gradient forces water and dissolved wastes to move back
- into the capillaries. Thus, water filtered out at the arteriole
- end of capillary beds is regained at the venule end with only
- a slight net loss in total water volume. The lymph system
- carries the extra fluid back into circulation.
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