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There is a balance between a number of compression settings. The encoder includes many predefined destination, video, and audio settings (profiles) that have already taken this balance into consideration. You can easily set up an encoding session using a predefined profile. However, if you want to customize the settings, then the following paragraphs provide information about the settings, including some of the tradeoffs to consider.
If you have set up a session that uses peak bit rate-based VBR encoding for audio, the peak buffer size for audio should be lower than the buffer size for video (if you are using CBR encoding for video) or peak buffer size for video (if you are using peak bit rate-based encoding for video).