Using effects in Premiere

You can add any effect to a clip at any time. If you don't like an effect, you can easily delete it. You can even apply the same effect multiple times to the same clip with different settings. For example, you can add multiple instances of the Equalize audio effect for situations when you would chain together multiple equalization hardware modules in a conventional audio studio.

By default, when you apply an effect to a clip, the effect is active for the duration of the clip. However, you can make the effect start and stop at specific times, or make the effect more or less intense over time, by using keyframes.

Applying Effects > Using effects in Premiere