Prairie Phlox is grouped with mesic prairie sand species here; however it is a species one would be very unlikely to encounter on "true tallgrass prairie". Prairie phlox (or downy phlox as it is often called) is also commonly present in oak savanna openings with Lithospermum croceum and lupines, as well as on the edge of xeric prairies.
This plant is considered the major host species for a moth, Schinia indiana, a candidate for federal listing. While the prairie phlox remains a fairly common wildflower in the Kankakee valley, the moth is listed as extirpated from Indiana.