The evaluation of a newly diagnosed male with breast cancer is similar to that of the female. All patients should undergo bilateral mammography. The metastatic work-up should include PA and lateral chest x-ray, bone scan and liver function studies. Other special studies should be considered such as chromosomal analysis if Klinefelter's syndrome is suspected.
The vast majority of cases are infiltrating ductal carcinoma although cases of lobular carcinoma have been reported (13). The reported range of estrogen receptor positivity in male breast cancer patients is 75- 100% versus 60 - 70% in female cases (3).