You can choose to never apply profiles to games.  If this setting is selected when you launch a game the profile for that game will never be applied.

1. In the WingMan Profiler main window, make sure the desired device is selected.

2. Click on the Options menu and select Global Profiler Settings. The Global Profiler Settings window will appear.

3. Select the option to disable applying profiles to games.

4. To accept the changes, click the OK button.

5. To discard the changes, click the Cancel button.

When you next launch any game, the profile for that game is not loaded into the driver.