Day 252 - 20 May 96 - Page 13
1 is a letter which is a page and a bit. Have you looked at
2 that letter?
3 A. Yes. I did look at the letter.
4
5 Q. And then there is a very short abstract from supplement a
6 to a magazine or journal called Circulation?
7 A. Yes.
8
9 Q. And the date of that was October 15th, 1995?
10 A. Yes.
11
12 Q. This was a somewhat larger sample of people. It was 20 as
13 opposed to 5. 20 healthy men and women, apparently. Now,
14 you have studied both the letter and the short abstract?
15 A. Yes, I have, yes.
16
17 Q. What comment do you have, or comments do you have, about
18 this piece of work?
19 A. Well, the number of subjects in this one were
20 satisfactory, to have 20 volunteers in a study like this is
21 useful. The subjects were subjected to two dietary
22 treatments, a diet which was based on healthy guidelines
23 and a high fat diet.
24
25 MR. JUSTICE BELL: What does the sign before the 40 percent in
26 the parentheses mean?
27
28 MR. MORRIS: Which page?
29
30 MR. JUSTICE BELL: On the letter.
31
32 MR. RAMPTON: You see, Professor, it says 'to the fat',
33 bracket, and then there is a 'to the 40 percent of total
34 calory intake' - what does that squiggly thing mean, that
35 'to the'?
36 A. A rise.
37
38 Q. A rise.
39
40 MR. JUSTICE BELL: It is like a 'c' for circa, is it?
41 A. Yes, it is the traditional way of saying I am not quite
42 sure of what the value was. It is around 40 percent The
43 two dietary treatments here which were referred to as high
44 fat and low fat are really not all that high in fat and all
45 that low in fat, in fact, one was 40 percent, which is
46 about the British average, and the other was about thirty
47 percent, which is hopefully our ultimate target, but it is
48 not very much lower. Now, in both cases neither of the
49 diets was monitored. People were simply instructed on what
50 to do when they went off for a month, they ate a high fat
51 traditional diet or they ate a healthy one, but we have no
52 idea whether they complied with the recommendations that
53 were made. There was no monitoring. But let us assume
54 they actually did that. Before they were given a
55 challenge, which was a high fat load, measurements were
56 made of their blood lipids which are supposed to reflect
57 risk of heart disease.
58
59 I find these very interesting because the little table that
60 is given here shows that there were no significant
