Day 039 - 20 Oct 94 - Page 40


     
     1
     2   MR. MORRIS:  I cannot see any other asterisks.  I think it must
     3        refer to that table.
     4        A.  It indicates that a 50-50 mixture of BHA and BHT were
     5        given which corresponds to 25 milligrams each of the two
     6        compounds.  I think the missing page from here is somewhere
     7        else in this collection and has been put back in the wrong
     8        place because I have seen it elsewhere.
     9
    10   MR. JUSTICE BELL:  Just tell us what it says, and any missing
    11        page must be given in due course?
    12        A.  No, the top of page 182 it does almost acknowledge
    13        there and say:  "This investigation revealed no positive
    14        reactions to the mixture of BHA and BHT", but cites other
    15        studies which have found reactions to BHA and BHT.
    16
    17   MR. MORRIS:  Just very quickly, what is the relevance of a
    18        "patch test" as opposed to ingestion?
    19        A.  It is more direct.
    20
    21   MS. STEEL:  Is a patch test a technique that is often used to
    22        determine what allergies that people may have?
    23        A.  Oh, yes.  Patch testing is often used to detect
    24        allergies and intolerance to compounds which may be
    25        ingested.  It is just that it provokes a reaction that much
    26        more rapidly and, therefore, reduces the amount of time
    27        people need to spend in the allergy clinic in that it
    28        reduces the duration of the test.
    29
    30   MR. MORRIS:  There are more details in the summary abstract at
    31        the front of both those last two tests that we looked at.
    32
    33   MS. STEEL:   We just brought that up because you mentioned about
    34        the fact that it was contact.
    35
    36   MR. JUSTICE BELL:  Yes, I understand why.
    37
    38   MS. STEEL:  We just wanted to clarify it.
    39
    40   MR. MORRIS:  That is all the papers we have for BHA.  BHA is
    41        banned in Japan; is that correct?
    42        A.  Well, I am not entirely clear what the position is.  It
    43        is slightly difficult because the relevant documents are in
    44        a language I do not read, but it is unclear to me whether
    45        there is a formally legislative ban or whether there is an
    46        informal understanding that the Japanese food industry will
    47        not use it.
    48
    49   Q.   What has provoked that?
    50        A.  Essentially, the results of the study by Ito and his 
    51        colleagues showing that it is a rodent carcinogen. 
    52 
    53   MR. JUSTICE BELL:  We have been told that before.
    54
    55   MR. MORRIS:  Yes, OK.
    56
    57   MR. JUSTICE BELL:  It was a Japanese study.
    58
    59   MR. MORRIS:  So, just one more thing on BHA.
    60

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