Day 036 - 13 Oct 94 - Page 20
1 polyunsaturated fat." That is what you have just drawn
2 our attention to, is it not, in the table?
3 A. Yes.
4
5 Q. "Other well-established breast cancer risk factors were
6 evident in this cohort of postmenopausal women and have
7 been reported previously; thus, this cohort was not
8 otherwise atypical with regard to breast cancer risk.
9
10 One perplexing finding concerns the effects of different
11 methods of adjustment for total energy intake.
12 Specifically, different procedures for energy adjustment
13 gave different impressions of the dietary fat-breast
14 cancer association, not so much in the strength of the
15 association, which was relatively weak in all analyses,
16 but in the shape of the exposure-outcome relationship."
17 I read that, Dr. Barnard, because I did not understand it
18 and I wondered if you could help us to explain it?
19 A. Let me take a look at that sentence and I would be
20 pleased to.
21
22 MR. JUSTICE BELL: I have a theory myself, but I am sure yours
23 is more valuable, Dr. Barnard. What occurred to me is it
24 is not so much the strength of the association which was
25 relatively weak in all analyses, but in the feature which
26 Mr. Rampton was putting to you, "the shape of the
27 exposure", that is, the intake, which quartile of intake
28 of fat you are in, as against the outcome, the
29 relationship between those two?
30 A. Yes, I am sure you are right.
31
32 MR. RAMPTON: That is what I hoped you would say; it is the
33 curious bumps and wobbles in the graph, if one drew it,
34 that they find puzzling; is that right?
35 A. Yes.
36
37 Q. Never mind which kind of analysis one used. Can I jump
38 on, because I am conscious of the need to save as much
39 time as can I.
40
41 MR. JUSTICE BELL: Are you going to another paper?
42
43 MR. RAMPTON: No, I am going to deal with this paper a little
44 bit further, if I may. I think it is in fairness to the
45 witness.
46
47 MR. JUSTICE BELL: We will have our break when we have finished
48 with this paper.
49
50 MR. RAMPTON: Very well, my Lord. Can you go to the top of
51 page -- it is the one after the tables -- 513.
52 A. Yes.
53
54 Q. 513 stamped at the bottom of the page. Again, I am doing
55 this because I think it fair to you that I should and
56 because it may help his Lordship in the end. It starts
57 right at the top of the left-hand column, "Two limitations
58 in the ability"; have you got that?
59 A. Yes.
60
