Day 036 - 13 Oct 94 - Page 47
1 the relative risk of breast cancer for women in the
2 highest quintile of consumption of saturated fat and
3 animal proteins were 3.0", I will skip the parenthetic
4 phrases for the moment, "and 2.9 respectively. A reduced
5 risk was found for women who derived less than 28 per cent
6 of calories from fat versus more than 36 per cent. A
7 similarly reduced risk was found for women who derived
8 less than 9.6 per cent of calories from saturated fat or
9 less than 5.9 per cent from animal proteins".
10
11 Skipping ahead to page 282, this part is perhaps a little
12 bit more responsive to your question.
13
14 MR. MORRIS: Wait until everyone has found it.
15
16 MR. JUSTICE BELL: What does the page look like because our
17 page numbers are -----
18 A. The top of the page is a chart; it says "table 4".
19 Skipping down to the very last partial paragraph, just the
20 last three lines of that page, it states (I would just
21 like to read one sentence): "Confounding by non-dietary
22 risk factors was first examined by evaluating correlation
23 coefficients between intakes of various nutrients and
24 potential confounders such as age at menarche, age at
25 menopause, age at first birth, height, weight, Quetelet
26 index", which is a synonym for the body mass index we
27 talked about earlier, "socioeconomic status, and marital
28 status."
29
30 Skipping down to about the tenth line is a sentence that
31 simply summarises the results of that analysis. It says:
32 "Adjustments for non-dietary variables did not
33 appreciably modify the RR" -- which means relative risk --
34 "estimates for the nutrients considered in our analysis."
35
36 So, in summary, what they have said so far is that they
37 found a clear cut relationship between higher-fat intake
38 and breast cancer. They then looked specifically and in a
39 very careful way at potential confounding factors,
40 menarche, age at menopause, age at first birth, marital
41 status, which was discussed earlier, and the others; even
42 after adjustment the dietary factors showed through to
43 have an important effect.
44
45 Skipping to just the next page under Discussion, the
46 second paragraph in the seventh line of that paragraph is
47 a summary statement which is as follows: "With nutrients
48 expressed" ----
49
50 MR. JUSTICE BELL: Where are you now?
51 A. Pardon me. Page 284, which is the page that has table
52 8 at the top.
53
54 Q. Where on the page?
55 A. Second paragraph under Discussion; the paragraph
56 begins with the word "analyses".
57
58 Q. "The results of this population-based case-control".
59
60 MR. MORRIS: The next paragraph.
