File menu > New
Keyboard > CTRL+N
New clears the contents of the current scene without changing system settings (viewport configuration, snap settings, Material Editor, background image, and so on).
Procedure
To create a new scene:
Choose File > New or press CTRL+N.
In the New Scene dialog, specify the types of objects to keep, if any.
Click OK.
Interface
The New Scene dialog has the following controls.
Keep Objects and Hierarchy: Keeps the objects and the hierarchical links between them, but removes any animation keys.
Keep Objects: Keeps the objects in the scene, but removes any links between them and any animation keys.
New All (Default): Clears content of the current scene.